A SECOND LOOK AT THE CRYSTAL STRUCTURES OF DROSOPHILA MELANOGASTER ACETYLCHOLINESTERASE IN COMPLEX WITH TACRINE DERIVATIVES PROVIDES INSIGHTS CONCERNING CATALYTIC INTERMEDIATES AND THE DESIGN OF SPECIFIC INSECTICIDES

Over recent decades, crystallographic software for data processing and structure refinement has improved dramatically, resulting in more accurate and detailed crystal structures.It is, therefore, sometimes valuable to have a second look at “old” diffraction data, especially when earlier interpretation of the electron density maps was ra

Three-dimensional morphological information about neural microcircuits is of high interest in neuroscience, but acquiring this information remains challenging.A promising new correlative technique for brain imaging is array tomography (Micheva and Smith, 2007), in which series of ultrathin brain sections are treated with fluorescent antibodies agai

The article presents the Islamic State as a Gift source of terrorist threats.In the eyes of ISIS fighters, the Western world is tantamount to moral corruption, and the lack of any values.By its actions, ISIS aims at pushing the followers of other religions out of the areas defined in the prophecies in the name of cleansing the world from evil.The a

A model of motion of a gas-dispersed medium in the presence of processes of nucleation, coagulation and phase transitions has been constructed.A homogeneous nucleation model is used to describe the nucleation process.It is believed that the process of Trousers cluster coagulation occurs due to their Brownian motion.The analysis of the solution of t